| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-09-09 | Minnesota Vikings (10-6) | 9 | New Orleans Saints (7-9) | 14 | - | - |
| 2010-09-12 | Miami Dolphins (7-9) | 15 | Buffalo Bills (6-10) | 10 | - | - |
| 2010-09-12 | Indianapolis Colts (11-5) | 24 | Houston Texans (12-4) | 34 | - | - |
| 2010-09-12 | Detroit Lions (4-12) | 14 | Chicago Bears (10-6) | 19 | - | - |
| 2010-09-12 | Atlanta Falcons (13-3) | 9 | Pittsburgh Steelers (8-8) | 15 | - | - |
| 2010-09-12 | Cleveland Browns (5-11) | 14 | Tampa Bay Buccaneers (7-9) | 17 | - | - |
| 2010-09-12 | Cincinnati Bengals (10-6) | 24 | New England Patriots (12-4) | 38 | - | - |
| 2010-09-12 | Denver Broncos (13-3) | 17 | Jacksonville Jaguars (2-14) | 24 | - | - |
| 2010-09-12 | Oakland Raiders (4-12) | 13 | Tennessee Titans (6-10) | 38 | - | - |
| 2010-09-12 | Carolina Panthers (7-9) | 18 | New York Giants (9-7) | 31 | - | - |
| 2010-09-12 | San Francisco 49ers (11-4-1) | 6 | Seattle Seahawks (11-5) | 31 | - | - |
| 2010-09-12 | Arizona Cardinals (5-11) | 17 | St. Louis Rams (7-8-1) | 13 | - | - |
| 2010-09-12 | Green Bay Packers (11-5) | 27 | Philadelphia Eagles (4-12) | 20 | - | - |
| 2010-09-12 | Dallas Cowboys (8-8) | 7 | Washington Commanders (10-6) | 13 | - | - |
| 2010-09-13 | Baltimore Ravens (10-6) | 10 | New York Jets (6-10) | 9 | - | - |
| 2010-09-13 | Los Angeles Chargers (7-9) | 14 | Kansas City Chefs (2-14) | 21 | - | - |
| Totals | 0/0 | 0/0 | ||||
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