| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-09-19 | Baltimore Ravens (14-2) | 10 | Cincinnati Bengals (2-14) | 15 | - | - |
| 2010-09-19 | Tampa Bay Buccaneers (7-9) | 20 | Carolina Panthers (5-11) | 7 | - | - |
| 2010-09-19 | Buffalo Bills (10-6) | 7 | Green Bay Packers (13-3) | 34 | - | - |
| 2010-09-19 | Miami Dolphins (5-11) | 14 | Minnesota Vikings (10-6) | 10 | - | - |
| 2010-09-19 | Chicago Bears (8-8) | 27 | Dallas Cowboys (8-8) | 20 | - | - |
| 2010-09-19 | Philadelphia Eagles (9-7) | 35 | Detroit Lions (3-12-1) | 32 | - | - |
| 2010-09-19 | Arizona Cardinals (5-10-1) | 7 | Atlanta Falcons (7-9) | 41 | - | - |
| 2010-09-19 | Kansas City Chefs (12-4) | 16 | Cleveland Browns (6-10) | 14 | - | - |
| 2010-09-19 | Pittsburgh Steelers (8-8) | 19 | Tennessee Titans (9-7) | 11 | - | - |
| 2010-09-19 | Seattle Seahawks (11-5) | 14 | Denver Broncos (7-9) | 31 | - | - |
| 2010-09-19 | St. Louis Rams () | 14 | Oakland Raiders (7-9) | 16 | - | - |
| 2010-09-19 | New England Patriots (12-4) | 14 | New York Jets (7-9) | 28 | - | - |
| 2010-09-19 | Houston Texans (10-6) | 30 | Washington Commanders (3-13) | 27 | - | - |
| 2010-09-19 | Jacksonville Jaguars (6-10) | 13 | Los Angeles Chargers (5-11) | 38 | - | - |
| 2010-09-19 | New York Giants (4-12) | 14 | Indianapolis Colts (7-9) | 38 | - | - |
| 2010-09-20 | New Orleans Saints (13-3) | 25 | San Francisco 49ers (13-3) | 22 | - | - |
| Totals | 0/0 | 0/0 | ||||
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