| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-16 | New York Giants (9-7) | 29 | Washington Commanders (5-11) | 30 | - | - |
| 2021-09-19 | New Orleans Saints (13-3) | 7 | Carolina Panthers (6-10) | 26 | - | - |
| 2021-09-19 | Cincinnati Bengals (9-7) | 17 | Chicago Bears (8-8) | 20 | - | - |
| 2021-09-19 | Houston Texans (10-6) | 21 | Cleveland Browns (4-12) | 31 | - | - |
| 2021-09-19 | Los Angeles Rams () | 27 | Indianapolis Colts (2-14) | 24 | - | - |
| 2021-09-19 | Denver Broncos (8-8) | 23 | Jacksonville Jaguars (5-11) | 13 | - | - |
| 2021-09-19 | Buffalo Bills (6-10) | 35 | Miami Dolphins (6-10) | 0 | - | - |
| 2021-09-19 | New England Patriots (13-3) | 25 | New York Jets (8-8) | 6 | - | - |
| 2021-09-19 | San Francisco 49ers (13-3) | 17 | Philadelphia Eagles (8-8) | 11 | - | - |
| 2021-09-19 | Las Vegas Raiders () | 26 | Pittsburgh Steelers (12-4) | 17 | - | - |
| 2021-09-19 | Minnesota Vikings (3-13) | 33 | Arizona Cardinals (8-8) | 34 | - | - |
| 2021-09-19 | Atlanta Falcons (10-6) | 25 | Tampa Bay Buccaneers (4-12) | 48 | - | - |
| 2021-09-19 | Dallas Cowboys (8-8) | 20 | Los Angeles Chargers (8-8) | 17 | - | - |
| 2021-09-19 | Tennessee Titans (9-7) | 33 | Seattle Seahawks (7-9) | 30 | - | - |
| 2021-09-19 | Kansas City Chefs (7-9) | 35 | Baltimore Ravens (12-4) | 36 | - | - |
| 2021-09-20 | Detroit Lions (10-6) | 17 | Green Bay Packers (15-1) | 35 | - | - |
| Totals | 0/0 | 0/0 | ||||
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