| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-09-19 | Baltimore Ravens (10-6) | 10 | Cincinnati Bengals (10-6) | 15 | - | - |
| 2010-09-19 | Tampa Bay Buccaneers (7-9) | 20 | Carolina Panthers (7-9) | 7 | - | - |
| 2010-09-19 | Buffalo Bills (6-10) | 7 | Green Bay Packers (11-5) | 34 | - | - |
| 2010-09-19 | Miami Dolphins (7-9) | 14 | Minnesota Vikings (10-6) | 10 | - | - |
| 2010-09-19 | Chicago Bears (10-6) | 27 | Dallas Cowboys (8-8) | 20 | - | - |
| 2010-09-19 | Philadelphia Eagles (4-12) | 35 | Detroit Lions (4-12) | 32 | - | - |
| 2010-09-19 | Arizona Cardinals (5-11) | 7 | Atlanta Falcons (13-3) | 41 | - | - |
| 2010-09-19 | Kansas City Chefs (2-14) | 16 | Cleveland Browns (5-11) | 14 | - | - |
| 2010-09-19 | Pittsburgh Steelers (8-8) | 19 | Tennessee Titans (6-10) | 11 | - | - |
| 2010-09-19 | Seattle Seahawks (11-5) | 14 | Denver Broncos (13-3) | 31 | - | - |
| 2010-09-19 | St. Louis Rams (7-8-1) | 14 | Oakland Raiders (4-12) | 16 | - | - |
| 2010-09-19 | New England Patriots (12-4) | 14 | New York Jets (6-10) | 28 | - | - |
| 2010-09-19 | Houston Texans (12-4) | 30 | Washington Commanders (10-6) | 27 | - | - |
| 2010-09-19 | Jacksonville Jaguars (2-14) | 13 | Los Angeles Chargers (7-9) | 38 | - | - |
| 2010-09-19 | New York Giants (9-7) | 14 | Indianapolis Colts (11-5) | 38 | - | - |
| 2010-09-20 | New Orleans Saints (7-9) | 25 | San Francisco 49ers (11-4-1) | 22 | - | - |
| Totals | 0/0 | 0/0 | ||||
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