| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-17 | Cleveland Browns (7-8-1) | 10 | Pittsburgh Steelers (9-6-1) | 28 | - | - |
| 2010-10-17 | New Orleans Saints (13-3) | 31 | Tampa Bay Buccaneers (5-11) | 6 | - | - |
| 2010-10-17 | Miami Dolphins (7-9) | 23 | Green Bay Packers (6-9-1) | 20 | - | - |
| 2010-10-17 | Los Angeles Chargers (12-4) | 17 | St. Louis Rams () | 20 | - | - |
| 2010-10-17 | Baltimore Ravens (10-6) | 20 | New England Patriots (11-5) | 23 | - | - |
| 2010-10-17 | Kansas City Chefs (12-4) | 31 | Houston Texans (11-5) | 35 | - | - |
| 2010-10-17 | Detroit Lions (6-10) | 20 | New York Giants (5-11) | 28 | - | - |
| 2010-10-17 | Atlanta Falcons (7-9) | 17 | Philadelphia Eagles (9-7) | 31 | - | - |
| 2010-10-17 | Seattle Seahawks (10-6) | 23 | Chicago Bears (12-4) | 20 | - | - |
| 2010-10-17 | Oakland Raiders (4-12) | 9 | San Francisco 49ers (4-12) | 17 | - | - |
| 2010-10-17 | New York Jets (4-12) | 24 | Denver Broncos (6-10) | 20 | - | - |
| 2010-10-17 | Dallas Cowboys (10-6) | 21 | Minnesota Vikings (8-7-1) | 24 | - | - |
| 2010-10-17 | Indianapolis Colts (10-6) | 27 | Washington Commanders (7-9) | 24 | - | - |
| 2010-10-18 | Tennessee Titans (9-7) | 30 | Jacksonville Jaguars (5-11) | 3 | - | - |
| Totals | 0/0 | 0/0 | ||||
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