| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-23 | Carolina Panthers (11-5) | 24 | Houston Texans (4-12) | 9 | - | - |
| 2021-09-26 | Washington Commanders (7-9) | 21 | Buffalo Bills (9-7) | 43 | - | - |
| 2021-09-26 | Chicago Bears (5-11) | 6 | Cleveland Browns (0-16) | 26 | - | - |
| 2021-09-26 | Baltimore Ravens (9-7) | 19 | Detroit Lions (9-7) | 17 | - | - |
| 2021-09-26 | Arizona Cardinals (8-8) | 31 | Jacksonville Jaguars (10-6) | 19 | - | - |
| 2021-09-26 | Los Angeles Chargers (9-7) | 30 | Kansas City Chefs (10-6) | 24 | - | - |
| 2021-09-26 | New Orleans Saints (11-5) | 28 | New England Patriots (13-3) | 13 | - | - |
| 2021-09-26 | Atlanta Falcons (10-6) | 17 | New York Giants (3-13) | 14 | - | - |
| 2021-09-26 | Cincinnati Bengals (7-9) | 24 | Pittsburgh Steelers (13-3) | 10 | - | - |
| 2021-09-26 | Indianapolis Colts (4-12) | 16 | Tennessee Titans (9-7) | 25 | - | - |
| 2021-09-26 | New York Jets (5-11) | 0 | Denver Broncos (5-11) | 26 | - | - |
| 2021-09-26 | Miami Dolphins (6-10) | 28 | Las Vegas Raiders () | 31 | - | - |
| 2021-09-26 | Tampa Bay Buccaneers (5-11) | 24 | Los Angeles Rams (11-5) | 34 | - | - |
| 2021-09-26 | Seattle Seahawks (9-7) | 17 | Minnesota Vikings (13-3) | 30 | - | - |
| 2021-09-26 | Green Bay Packers (7-9) | 30 | San Francisco 49ers (6-10) | 28 | - | - |
| 2021-09-27 | Philadelphia Eagles (13-3) | 21 | Dallas Cowboys (9-7) | 41 | - | - |
| Totals | 0/0 | 0/0 | ||||
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