| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-09 | Dallas Cowboys (13-3) | 29 | Tampa Bay Buccaneers (9-7) | 31 | - | - |
| 2021-09-12 | Philadelphia Eagles (8-8) | 32 | Atlanta Falcons (4-12) | 6 | - | - |
| 2021-09-12 | Pittsburgh Steelers (10-6) | 23 | Buffalo Bills (7-9) | 16 | - | - |
| 2021-09-12 | New York Jets (4-12) | 14 | Carolina Panthers (7-9) | 19 | - | - |
| 2021-09-12 | Minnesota Vikings (8-8) | 24 | Cincinnati Bengals (7-9) | 27 | - | - |
| 2021-09-12 | San Francisco 49ers (5-11) | 41 | Detroit Lions (7-9) | 33 | - | - |
| 2021-09-12 | Jacksonville Jaguars (11-5) | 21 | Houston Texans (8-8) | 37 | - | - |
| 2021-09-12 | Seattle Seahawks (10-6) | 28 | Indianapolis Colts (13-3) | 16 | - | - |
| 2021-09-12 | Arizona Cardinals (8-8) | 38 | Tennessee Titans (10-6) | 13 | - | - |
| 2021-09-12 | Los Angeles Chargers (11-5) | 20 | Washington Commanders (9-7) | 16 | - | - |
| 2021-09-12 | Cleveland Browns (10-6) | 29 | Kansas City Chefs (4-12) | 33 | - | - |
| 2021-09-12 | Miami Dolphins (1-15) | 17 | New England Patriots (16-0) | 16 | - | - |
| 2021-09-12 | Green Bay Packers (13-3) | 3 | New Orleans Saints (7-9) | 38 | - | - |
| 2021-09-12 | Denver Broncos (7-9) | 27 | New York Giants (10-6) | 13 | - | - |
| 2021-09-12 | Chicago Bears (7-9) | 14 | Los Angeles Rams () | 34 | - | - |
| 2021-09-13 | Baltimore Ravens (5-11) | 27 | Las Vegas Raiders () | 33 | - | - |
| Totals | 0/0 | 0/0 | ||||
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