| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-10 | Tampa Bay Buccaneers (5-11) | 24 | Cincinnati Bengals (6-10) | 21 | - | - |
| 2010-10-10 | Atlanta Falcons (7-9) | 20 | Cleveland Browns (7-8-1) | 10 | - | - |
| 2010-10-10 | New York Giants (5-11) | 34 | Houston Texans (11-5) | 10 | - | - |
| 2010-10-10 | Kansas City Chefs (12-4) | 9 | Indianapolis Colts (10-6) | 19 | - | - |
| 2010-10-10 | Green Bay Packers (6-9-1) | 13 | Washington Commanders (7-9) | 16 | - | - |
| 2010-10-10 | Jacksonville Jaguars (5-11) | 36 | Buffalo Bills (6-10) | 26 | - | - |
| 2010-10-10 | Denver Broncos (6-10) | 17 | Baltimore Ravens (10-6) | 31 | - | - |
| 2010-10-10 | Chicago Bears (12-4) | 23 | Carolina Panthers (7-9) | 6 | - | - |
| 2010-10-10 | St. Louis Rams () | 6 | Detroit Lions (6-10) | 44 | - | - |
| 2010-10-10 | New Orleans Saints (13-3) | 20 | Arizona Cardinals (3-13) | 30 | - | - |
| 2010-10-10 | Los Angeles Chargers (12-4) | 27 | Oakland Raiders (4-12) | 35 | - | - |
| 2010-10-10 | Tennessee Titans (9-7) | 34 | Dallas Cowboys (10-6) | 27 | - | - |
| 2010-10-10 | Philadelphia Eagles (9-7) | 27 | San Francisco 49ers (4-12) | 24 | - | - |
| 2010-10-11 | Minnesota Vikings (8-7-1) | 20 | New York Jets (4-12) | 29 | - | - |
| Totals | 0/0 | 0/0 | ||||
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