| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-10 | Tampa Bay Buccaneers (8-9) | 24 | Cincinnati Bengals (12-4) | 21 | - | - |
| 2010-10-10 | Atlanta Falcons (7-10) | 20 | Cleveland Browns (7-10) | 10 | - | - |
| 2010-10-10 | New York Giants (9-7-1) | 34 | Houston Texans (3-13-1) | 10 | - | - |
| 2010-10-10 | Kansas City Chefs (14-3) | 9 | Indianapolis Colts (4-12-1) | 19 | - | - |
| 2010-10-10 | Green Bay Packers (8-9) | 13 | Washington Commanders (8-8-1) | 16 | - | - |
| 2010-10-10 | Jacksonville Jaguars (9-8) | 36 | Buffalo Bills (13-3) | 26 | - | - |
| 2010-10-10 | Denver Broncos (5-12) | 17 | Baltimore Ravens (10-7) | 31 | - | - |
| 2010-10-10 | Chicago Bears (3-14) | 23 | Carolina Panthers (7-10) | 6 | - | - |
| 2010-10-10 | St. Louis Rams () | 6 | Detroit Lions (9-8) | 44 | - | - |
| 2010-10-10 | New Orleans Saints (7-10) | 20 | Arizona Cardinals (4-13) | 30 | - | - |
| 2010-10-10 | Los Angeles Chargers (10-7) | 27 | Oakland Raiders () | 35 | - | - |
| 2010-10-10 | Tennessee Titans (7-10) | 34 | Dallas Cowboys (12-5) | 27 | - | - |
| 2010-10-10 | Philadelphia Eagles (14-3) | 27 | San Francisco 49ers (13-4) | 24 | - | - |
| 2010-10-11 | Minnesota Vikings (13-4) | 20 | New York Jets (7-10) | 29 | - | - |
| Totals | 0/0 | 0/0 | ||||
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