| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-30 | Jacksonville Jaguars (7-9) | 21 | Cincinnati Bengals (10-6) | 24 | - | - |
| 2021-10-03 | Washington Commanders (4-12) | 34 | Atlanta Falcons (9-7) | 30 | - | - |
| 2021-10-03 | Houston Texans (9-7) | 0 | Buffalo Bills (6-10) | 40 | - | - |
| 2021-10-03 | Detroit Lions (2-14) | 14 | Chicago Bears (7-9) | 24 | - | - |
| 2021-10-03 | Carolina Panthers (8-8) | 28 | Dallas Cowboys (11-5) | 36 | - | - |
| 2021-10-03 | Indianapolis Colts (14-2) | 27 | Miami Dolphins (7-9) | 17 | - | - |
| 2021-10-03 | Cleveland Browns (5-11) | 14 | Minnesota Vikings (12-4) | 7 | - | - |
| 2021-10-03 | New York Giants (8-8) | 27 | New Orleans Saints (13-3) | 21 | - | - |
| 2021-10-03 | Tennessee Titans (8-8) | 24 | New York Jets (9-7) | 27 | - | - |
| 2021-10-03 | Kansas City Chefs (4-12) | 42 | Philadelphia Eagles (11-5) | 30 | - | - |
| 2021-10-03 | Arizona Cardinals (10-6) | 37 | Los Angeles Rams () | 20 | - | - |
| 2021-10-03 | Seattle Seahawks (5-11) | 28 | San Francisco 49ers (8-8) | 21 | - | - |
| 2021-10-03 | Baltimore Ravens (9-7) | 23 | Denver Broncos (8-8) | 7 | - | - |
| 2021-10-03 | Pittsburgh Steelers (9-7) | 17 | Green Bay Packers (11-5) | 27 | - | - |
| 2021-10-03 | Tampa Bay Buccaneers (3-13) | 19 | New England Patriots (10-6) | 17 | - | - |
| 2021-10-04 | Las Vegas Raiders () | 14 | Los Angeles Chargers (13-3) | 28 | - | - |
| Totals | 0/0 | 0/0 | ||||
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