| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-09 | Dallas Cowboys (6-10) | 29 | Tampa Bay Buccaneers (11-5) | 31 | Buccaneers | 8 |
| 2021-09-12 | Philadelphia Eagles (4-11-1) | 32 | Atlanta Falcons (4-12) | 6 | Falcons | 3 |
| 2021-09-12 | Pittsburgh Steelers (12-4) | 23 | Buffalo Bills (13-3) | 16 | Bills | 2 |
| 2021-09-12 | New York Jets (2-14) | 14 | Carolina Panthers (5-11) | 19 | Panthers | 14 |
| 2021-09-12 | Minnesota Vikings (7-9) | 24 | Cincinnati Bengals (4-11-1) | 27 | Vikings | 11 |
| 2021-09-12 | San Francisco 49ers (6-10) | 41 | Detroit Lions (5-11) | 33 | 49ers | 13 |
| 2021-09-12 | Jacksonville Jaguars (1-15) | 21 | Houston Texans (4-12) | 37 | Texans | 1 |
| 2021-09-12 | Seattle Seahawks (12-4) | 28 | Indianapolis Colts (11-5) | 16 | Seahawks | 6 |
| 2021-09-12 | Arizona Cardinals (8-8) | 38 | Tennessee Titans (11-5) | 13 | Titans | 5 |
| 2021-09-12 | Los Angeles Chargers (7-9) | 20 | Washington Commanders (7-9) | 16 | Commanders | 12 |
| 2021-09-12 | Cleveland Browns (11-5) | 29 | Kansas City Chefs (14-2) | 33 | Chefs | 15 |
| 2021-09-12 | Miami Dolphins (10-6) | 17 | New England Patriots (7-9) | 16 | Patriots | 10 |
| 2021-09-12 | Green Bay Packers (13-3) | 3 | New Orleans Saints (12-4) | 38 | Packers | 9 |
| 2021-09-12 | Denver Broncos (5-11) | 27 | New York Giants (6-10) | 13 | Broncos | 4 |
| 2021-09-12 | Chicago Bears (8-8) | 14 | Los Angeles Rams (10-6) | 34 | Rams | 16 |
| 2021-09-13 | Baltimore Ravens (11-5) | 27 | Las Vegas Raiders () | 33 | Ravens | 7 |
| Totals | 8/16 | 77/136 | ||||
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