| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-09-23 | Carolina Panthers (2-15) | 24 | Houston Texans (10-7) | 9 | - | - |
| 2021-09-26 | Washington Commanders (4-13) | 21 | Buffalo Bills (11-6) | 43 | - | - |
| 2021-09-26 | Chicago Bears (7-10) | 6 | Cleveland Browns (11-6) | 26 | - | - |
| 2021-09-26 | Baltimore Ravens (13-4) | 19 | Detroit Lions (12-5) | 17 | - | - |
| 2021-09-26 | Arizona Cardinals (4-13) | 31 | Jacksonville Jaguars (9-8) | 19 | - | - |
| 2021-09-26 | Los Angeles Chargers (5-12) | 30 | Kansas City Chefs (11-6) | 24 | - | - |
| 2021-09-26 | New Orleans Saints (9-8) | 28 | New England Patriots (4-13) | 13 | - | - |
| 2021-09-26 | Atlanta Falcons (7-10) | 17 | New York Giants (6-11) | 14 | - | - |
| 2021-09-26 | Cincinnati Bengals (9-8) | 24 | Pittsburgh Steelers (10-7) | 10 | - | - |
| 2021-09-26 | Indianapolis Colts (9-8) | 16 | Tennessee Titans (6-11) | 25 | - | - |
| 2021-09-26 | New York Jets (7-10) | 0 | Denver Broncos (8-9) | 26 | - | - |
| 2021-09-26 | Miami Dolphins (11-6) | 28 | Las Vegas Raiders (8-9) | 31 | - | - |
| 2021-09-26 | Tampa Bay Buccaneers (9-8) | 24 | Los Angeles Rams (10-7) | 34 | - | - |
| 2021-09-26 | Seattle Seahawks (9-8) | 17 | Minnesota Vikings (7-10) | 30 | - | - |
| 2021-09-26 | Green Bay Packers (9-8) | 30 | San Francisco 49ers (12-5) | 28 | - | - |
| 2021-09-27 | Philadelphia Eagles (11-6) | 21 | Dallas Cowboys (12-5) | 41 | - | - |
| Totals | 0/0 | 0/0 | ||||
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