| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-10-14 | Tampa Bay Buccaneers (3-13) | 28 | Philadelphia Eagles (11-5) | 22 | - | - |
| 2021-10-17 | Miami Dolphins (7-9) | 20 | Jacksonville Jaguars (7-9) | 23 | - | - |
| 2021-10-17 | Los Angeles Chargers (13-3) | 6 | Baltimore Ravens (9-7) | 34 | - | - |
| 2021-10-17 | Minnesota Vikings (12-4) | 34 | Carolina Panthers (8-8) | 28 | - | - |
| 2021-10-17 | Green Bay Packers (11-5) | 24 | Chicago Bears (7-9) | 14 | - | - |
| 2021-10-17 | Cincinnati Bengals (10-6) | 34 | Detroit Lions (2-14) | 11 | - | - |
| 2021-10-17 | Houston Texans (9-7) | 3 | Indianapolis Colts (14-2) | 31 | - | - |
| 2021-10-17 | Los Angeles Rams () | 38 | New York Giants (8-8) | 11 | - | - |
| 2021-10-17 | Kansas City Chefs (4-12) | 31 | Washington Commanders (4-12) | 13 | - | - |
| 2021-10-17 | Arizona Cardinals (10-6) | 37 | Cleveland Browns (5-11) | 14 | - | - |
| 2021-10-17 | Las Vegas Raiders () | 34 | Denver Broncos (8-8) | 24 | - | - |
| 2021-10-17 | Dallas Cowboys (11-5) | 35 | New England Patriots (10-6) | 29 | - | - |
| 2021-10-17 | Seattle Seahawks (5-11) | 20 | Pittsburgh Steelers (9-7) | 23 | - | - |
| 2021-10-18 | Buffalo Bills (6-10) | 31 | Tennessee Titans (8-8) | 34 | - | - |
| Totals | 0/0 | 0/0 | ||||
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