| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2010-10-10 | Tampa Bay Buccaneers (5-11) | 24 | Cincinnati Bengals (7-9) | 21 | - | - |
| 2010-10-10 | Atlanta Falcons (10-6) | 20 | Cleveland Browns (0-16) | 10 | - | - |
| 2010-10-10 | New York Giants (3-13) | 34 | Houston Texans (4-12) | 10 | - | - |
| 2010-10-10 | Kansas City Chefs (10-6) | 9 | Indianapolis Colts (4-12) | 19 | - | - |
| 2010-10-10 | Green Bay Packers (7-9) | 13 | Washington Commanders (7-9) | 16 | - | - |
| 2010-10-10 | Jacksonville Jaguars (10-6) | 36 | Buffalo Bills (9-7) | 26 | - | - |
| 2010-10-10 | Denver Broncos (5-11) | 17 | Baltimore Ravens (9-7) | 31 | - | - |
| 2010-10-10 | Chicago Bears (5-11) | 23 | Carolina Panthers (11-5) | 6 | - | - |
| 2010-10-10 | St. Louis Rams () | 6 | Detroit Lions (9-7) | 44 | - | - |
| 2010-10-10 | New Orleans Saints (11-5) | 20 | Arizona Cardinals (8-8) | 30 | - | - |
| 2010-10-10 | Los Angeles Chargers (9-7) | 27 | Oakland Raiders (6-10) | 35 | - | - |
| 2010-10-10 | Tennessee Titans (9-7) | 34 | Dallas Cowboys (9-7) | 27 | - | - |
| 2010-10-10 | Philadelphia Eagles (13-3) | 27 | San Francisco 49ers (6-10) | 24 | - | - |
| 2010-10-11 | Minnesota Vikings (13-3) | 20 | New York Jets (5-11) | 29 | - | - |
| Totals | 0/0 | 0/0 | ||||
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