| Date | Away | Score | Home | Score | Pick | Confidence |
|---|---|---|---|---|---|---|
| 2021-11-25 | Chicago Bears (3-14) | 16 | Detroit Lions (9-8) | 14 | Lions | 2 |
| 2021-11-25 | Las Vegas Raiders (6-11) | 36 | Dallas Cowboys (12-5) | 33 | Cowboys | 16 |
| 2021-11-25 | Buffalo Bills (13-3) | 31 | New Orleans Saints (7-10) | 6 | Bills | 15 |
| 2021-11-28 | Pittsburgh Steelers (9-8) | 10 | Cincinnati Bengals (12-4) | 41 | Bengals | 14 |
| 2021-11-28 | New York Jets (7-10) | 21 | Houston Texans (3-13-1) | 14 | Texans | 3 |
| 2021-11-28 | Tampa Bay Buccaneers (8-9) | 38 | Indianapolis Colts (4-12-1) | 31 | Buccaneers | 6 |
| 2021-11-28 | Atlanta Falcons (7-10) | 21 | Jacksonville Jaguars (9-8) | 14 | Jaguars | 5 |
| 2021-11-28 | Carolina Panthers (7-10) | 10 | Miami Dolphins (9-8) | 33 | Panthers | 12 |
| 2021-11-28 | Tennessee Titans (7-10) | 13 | New England Patriots (8-9) | 36 | Patriots | 13 |
| 2021-11-28 | Philadelphia Eagles (14-3) | 7 | New York Giants (9-7-1) | 13 | Eagles | 10 |
| 2021-11-28 | Los Angeles Chargers (10-7) | 13 | Denver Broncos (5-12) | 28 | Broncos | 11 |
| 2021-11-28 | Los Angeles Rams (5-12) | 28 | Green Bay Packers (8-9) | 36 | Packers | 7 |
| 2021-11-28 | Minnesota Vikings (13-4) | 26 | San Francisco 49ers (13-4) | 34 | 49ers | 8 |
| 2021-11-28 | Cleveland Browns (7-10) | 10 | Baltimore Ravens (10-7) | 16 | Ravens | 9 |
| 2021-11-29 | Seattle Seahawks (9-8) | 15 | Washington Commanders (8-8-1) | 17 | Commanders | 4 |
| Totals | 9/15 | 87/135 | ||||
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